Mateusz Wietecha, PhD, DMD

Humans have a remarkable ability to heal after injury, involving coordinated actions of many cell populations and their products. Cancer encapsulates the entire healing process becoming dysregulated, and it has been described as a “wound that fails to heal”. Oral mucosa has greater regenerative potential than skin, but oral tumors are more aggressive than their more common counterparts in the skin. We investigate such parallels between healing and cancer formation using multi-omics and imaging.