Translational Pathology Shared Resource (TPSR)

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The Translational Pathology Shared Resource (TPSR) was established in 2011. It provides University of Illinois Cancer Center (UICC) members with access to a comprehensive range of services involving the analysis of animal model and human tissue samples. These services include basic and advanced histological techniques, chemical staining and immunohistochemistry, digital slide scanning, image analysis, tissue microarray design and construction, and laser capture microdissection. In addition, it provides consultation for projects from pathologists with both clinical and laboratory animal expertise.

Meet Our Team

Andre Kajdacsy Balla, MD, PhD, TPSR Leader

Professor of Pathology, board-certified clinical and surgical pathologist began this position in September 2022, Dr. Balla has provided surgical pathology support to TPSR and UICC members since 2003 as Director of the Division of Transdisciplinary Pathology in the Department of Pathology. He has participated as a PI or as a collaborator in multiple grants on cancer biology and novel imaging methods such as FT-IR spectroscopy and Spatial Light Interference Microscopy.

Eileen Brister, PhD, Research Tissue Imaging Core 

Dr. Brister is a Research Assistant Professor in the Department of Pathology with expertise in imaging and image processing. They manage the day-to-day operations of the Research Tissue Imaging Core and develop digital pathology methods for reproducible, automated analysis of tissue morphology and biomarkers in human and animal tissues. They are available for consultations regarding tissue imaging and digital analysis approaches.

Subhasis Das, MSc, PhD
Patient-Derived Models Laboratory

Dr. Das is a Research Assistant Professor in the Department of Surgery with broad expertise in developing preclinical cancer models, including PDXs, PDOs, and metastatic models. He has established the patient-derived models’ core lab and plays a leadership role in creating and performing experiments using patient-derived models. He provides direct service and consultation to investigators studying potential drug responses.

Maria Sverdlov, PhD, MS
Research Histology

Dr. Sverdlov, a Research Assistant Professor in Pathology, joined TPSR in 2016 after completing postdoctoral studies in pathology at Northwestern and UIC. She oversees the day-to-day operations of the research histology core and develops and validates novel and complex immunohistochemical and molecular (RNAscope) assays on human and animal tissue. She is available for consultations on sample preparation and experimental assay design.

Photo of Martin Bosland

Maarten Bosland DVM, PhD,
Animal Pathology Consultant

Dr. Bosland serves as one of the primary pathology consultants available to TPSR clients and staff. He is a Professor of Pathology (Emeritus) who is trained in veterinary pathology with special expertise in laboratory animal models. He is available for consultation on interpreting complex histology in laboratory animals, including phenotypic characterization of genetically manipulated models.

Peter Gann, MD, ScD

A Professor of Pathology (Emeritus), Dr. Gann has 25+ years of experience in cancer biomarker research, including the development of tissue-based biomarkers and digital imaging techniques for quantitative analysis. He established the Division of Pathology Research at UIC in 2006, serving as the TPSR Director from 2016 to 2022. He is a consultant in study design, cancer biology, and tissue imaging new technologies.

Virgilia Macias, MD, TMA/LCM

Dr. Macias is a research surgical pathologist with training in oncologic surgical pathology, electron microscopy, and immunohistochemistry. She is currently a Research Assistant Professor in the Division of Transdisciplinary Pathology at UIC. She has been conducting translational research for 20+ years. In addition to LCM and TMA services, she performs central histology reviews of pathological entities.

TPSR Major Services

The TPSR supports its users through consultation, direct services, and relevant training and education.



Direct Services



TMA Services

Patient-Derived Models

Training & Education

Contact Us

For more information or questions related to the University of Illinois Cancer Center shared resources, please email

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